Symbol
Name
ID

Ift172
intraflagellar transport 172
MGI:2682064

Phenotype annotations related to nervous system

Darker colors indicate more annotations

Human Phenotypes	Oculomotor apraxia	Hydrocephalus	Ventriculomegaly	Cerebellar vermis hypoplasia	Increased intracranial pressure	Delayed speech and language development	Intellectual disability	Intellectual disability, borderline	Global developmental delay
Disease(s) Associated with IFT172	Oculomotor apraxia	Hydrocephalus	Ventriculomegaly	Cerebellar vermis hypoplasia	Increased intracranial pressure	Delayed speech and language development	Intellectual disability	Intellectual disability, borderline	Global developmental delay
Bardet-Biedl syndrome 20
short-rib thoracic dysplasia 10 with or without polydactyly

Mouse Phenotypes

abnormal neural tube morphology

abnormal embryonic neuroepithelium morphology

abnormal floor plate morphology

abnormal neural tube closure

open neural tube

abnormal rhombomere morphology

abnormal brain development

holoprosencephaly

hydrocephaly

enlarged brain ventricles

abnormal diencephalon morphology

abnormal telencephalon morphology

exencephaly

abnormal photoreceptor outer segment morphology

abnormal photoreceptor outer segment disc membrane morphology

short photoreceptor outer segment

disorganized photoreceptor outer segment

photoreceptor outer segment degeneration

abnormal spinal cord morphology

Availability

Mouse Genotype

Ift172^avc1/Ift172^avc1

Ift172^tm1.2Rama/Ift172^tm1.2Rama

Ift172^tm1Lmgd/Ift172^tm1Lmgd

Ift172^{tm2b(EUCOMM)Hmgu}/Ift172^{tm2b(EUCOMM)Hmgu}

Ift172^wim/Ift172^wim

Ift172^tm1.1Rama/Ift172^tm1.1Rama
Tg(Rho-icre)1Ck/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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